Helen Pickersgill, PhD

Editorial Experience

Independent Scientific Editor, helenpickersgill.com (2004-present)

Manuscript and grant editing and consulting for a wide range of scientists from institutes including:

  • University of California, San Francisco (UCSF), USA
  • The Whitehead Institute, USA
  • INSERM, Marseille, Fr
  • Netherlands Cancer Institute (NKI), NL
  • Tsinghua University, Beijing, CN

Scientific Editor, Science. (2008-2013)

  • Handled manuscripts on topics including molecular biology, developmental biology and neurobiology by managing peer review and making editorial decisions.
  • Commissioned and edited Perspectives articles.
  • Edited manuscripts for publication.
  • Wrote Editors’ Choice.

Scientific Editor, Science Translational Medicine (2010)

  • Handled and edited biomedical manuscripts.

Scientific Editor, Developmental Cell. (2007)

  • Handled the peer review and evaluation of over 100 manuscripts in cell and developmental biology.
  • Commissioned review articles and edited for clarity.

Managing Editor, Center for Molecular Medicine (CeMM) Austria. (2008-2014)

Scientific Annual Report.


Author of science-related articles (2004-2005)

Naked Scientists.com

LabLit.com


Academic Experience

Post-doctoral Associate, 2006-2007

Whitehead Institute, Cambridge, USA

Cancer RNAi and compound screens in human cells.

Dr. T Brummelkamp.


Marie Curie Post-doctoral Fellow, 2001-2006

Netherlands Cancer Institute (NKI), NL

Genome-wide DNA-binding screens to characterize chromatin organization in relation to gene expression.

Dr. M Fornerod


Ph.D. Cell Biology,  2001

Paterson Institute, UK

EM structure and function of the nuclear pore complex.

Professor T Allen


BSc (Hon)Molecular Biology, 1998

University of Manchester, UK


Publications

Nucleoporins directly stimulate expression of developmental and cell cycle genes inside the nucleoplasm. Kalverda, B.,*, Pickersgill, H.,*, Shloma, V.V., Fornerod, M. Cell (2010) 140(3):360-71.

Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF. Wellbrock, C., Rana, S., Paterson, H., Pickersgill, H., Brummelkamp, T., Marais, R. PLoS One (2008). 3(7):e2743.

Characterization of the Drosophila melanogaster genome at the nuclear lamina.  Pickersgill, H., Kalverda, B., de Wit, E., Talhout, W., Fornerod, M., van Steensel, B. Nat Genet. (2006) 38(9):1005-14.

Nup214-Nup88 nucleoporin subcomplex is required for CRM1-mediated 60 S preribosomal nuclear export. Bernad, R., Engelsma, D., Sanderson, H., Pickersgill, H., Fornerod, M. J Biol Chem. (2006) 281 (28): 19378 -86.

Nup358/RanBP2 attaches to the nuclear pore complex via association with Nup88 and Nup214/CAN and plays a supporting role in CRM1-mediated nuclear protein export. Bernad, R., van der Velde, H., Fornerod, M.,Pickersgill, H. Mol Cell Biol. (2004) 24(6): 2373-84.

The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Walther, T.C., Alves, A.,Pickersgill, H., Loïodice, I., Hetzer, M., Galy, V., Hülsmann, B.B., Köcher, T., Wilm, M., Allen, T., Mattaj, I.W., Doye, V.Cell (2003) 113(2): 195-206.

The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import. Walther, T.C.*, Pickersgill, H.S.*, Cordes, V.C., Goldberg, M.W., Allen, T.D., Mattaj, I.W., Fornerod, M. J Cell Biol. (2002) 158(1): 63-77.

The nucleoporin Nup153 is required for nuclear pore basket formation, nuclear pore complex anchoring and import of a subset of nuclear proteins. Walther, T.C., Fornerod, M., Pickersgill, H., Goldberg, M., Allen, T.D., Mattaj, I.W. EMBO J. (2001) 20(20): 5703-14.

* Equal contribution.


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